Table 2.
Potential pleiotropic genes identified by both metaCCA analysis and VEGAS2 analysis for six traits.
| Gene | p.meta | p.f | p.oa | p.pso | p.ra | p.sp | p.op |
|---|---|---|---|---|---|---|---|
| PLCL2 | 3.15E-06 | 6.63E-01 | 3.78E-01 | 7.59E-02 | 1.00E-06 | 8.89E-02 | 8.51E-01 |
| DAP | 2.25E-06 | 4.80E-01 | 6.72E-01 | 2.72E-01 | 1.00E-06 | 9.89E-02 | 6.24E-01 |
| COG6 | 2.33E-07 | 4.52E-02 | 9.55E-01 | 6.84E-01 | 1.00E-06 | 4.00E-01 | 3.74E-01 |
| ARID5B | 3.40E-08 | 2.86E-01 | 4.06E-01 | 2.10E-01 | 1.00E-06 | 9.30E-01 | 5.17E-01 |
| IRF5 | 2.48E-08 | 1.44E-02 | 4.86E-01 | 5.10E-02 | 1.00E-06 | 5.38E-01 | 3.56E-01 |
| CCDC170 | 8.76E-09 | 1.00E-06 | 9.87E-01 | 2.38E-01 | 7.96E-01 | 7.84E-01 | 1.00E-06 |
| SLC44A4 | 5.16E-09 | 6.77E-01 | 5.22E-01 | 1.00E-06 | 1.00E-06 | 5.98E-01 | 2.88E-03 |
| CCR6 | 1.96E-09 | 4.35E-02 | 7.30E-01 | 7.52E-01 | 1.00E-06 | 3.95E-02 | 2.38E-01 |
| UQCC2 | 7.77E-10 | 5.12E-01 | 4.12E-01 | 6.36E-03 | 1.00E-06 | 8.48E-01 | 2.54E-02 |
| MAGI3 | 1.91E-16 | 5.85E-02 | 8.26E-01 | 9.97E-01 | 1.00E-06 | 4.18E-01 | 7.49E-02 |
| DCLRE1B | 7.52E-18 | 4.87E-01 | 6.22E-01 | 9.42E-01 | 1.00E-06 | 6.83E-01 | 2.89E-02 |
| SYNGAP1 | 7.38E-19 | 8.26E-01 | 1.44E-01 | 7.84E-01 | 1.00E-06 | 4.60E-01 | 6.54E-01 |
| AFF3 | 7.18E-25 | 7.46E-01 | 5.12E-01 | 3.35E-03 | 2.00E-06 | 5.79E-01 | 1.86E-01 |
| RSBN1 | 3.54E-34 | 1.79E-01 | 1.00E+00 | 9.45E-01 | 1.00E-06 | 3.10E-01 | 6.27E-02 |
| HLA-DOA | 2.80E-55 | 9.13E-01 | 3.72E-01 | 2.22E-03 | 1.00E-06 | 5.96E-01 | 2.12E-01 |
| HLA-DOB | 1.31E-66 | 1.56E-01 | 6.16E-01 | 1.00E-06 | 1.00E-06 | 2.05E-01 | 9.83E-01 |
| ANKRD55 | 2.28E-67 | 6.29E-01 | 5.50E-01 | 2.71E-01 | 1.00E-06 | 6.08E-01 | 8.45E-01 |
| TAP2 | 2.60E-109 | 1.19E-01 | 5.89E-01 | 1.00E-06 | 1.00E-06 | 6.96E-01 | 7.53E-01 |
| C2 | 3.46E-120 | 5.97E-01 | 3.19E-01 | 1.00E-06 | 1.00E-06 | 2.68E-01 | 1.40E-03 |
Note: Bold numbers indicate a significant adjusted p-value (p < 0.05) for the VEGAS2 test, and the bold text indicates genes related to more than one trait in the VEGAS2 test.