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The percentage difference of morning-evening variation in clock gene expression for subjects with and without OSA. (A) expression of HIF1α increased by 23% in subjects with OSA when compared with those without OSA (P = 0.008) (B and C) Relative gene expression of Timeless (R = −0.223, P = 0.038) and Cry2 (R= −0.348, P = 0.012) in subjects with OSA decreased with increasing AHI. Data represent means ± SEM. **P < 0.01.
