Skip to main content
. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Nat Med. 2022 Jan;28(1):9–11. doi: 10.1038/s41591-021-01617-x

Fig. 1 |. Study schematic for I-SPY COVID.

Fig. 1 |

The I-SPy COVID adaptive platform trial is a trial for patients with severe COVID-19 in which up to four agents are evaluated in parallel on a backbone of standard of care. Participants who do not wish to participate in the randomized cohort or who meet exclusion criteria are enrolled in an observational arm (per a waiver of informed consent from the Institutional review Board) in which clinical and outcomes data are collected through medical records.