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. 2022 Mar 1;12:762130. doi: 10.3389/fendo.2021.762130

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Copyright © 2022 Hanna, Ahdoot, Kalantar-Zadeh, Ghobry and Kurtz

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nephron molecular calcium handling-loop of Henle: ATPase, adenosine triphosphatase; CaSR, calcium sensing receptor; Ca²⁺, calcium; Cl^-, chloride; H20, water; K⁺, potassium; mV, millivolt; Na⁺, sodium; NKCC2, sodium potassium two chloride transporter; ROMK, apical renal outer medullary potassium channel; TAL, thick ascending of Henle; ClC-Ka, chloride channel kidney A; ClC-Kb, chloride channel kidney B; MAGED-2, melanoma-associated antigen D2.