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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Prog Retin Eye Res. 2021 Mar 26;85:100967. doi: 10.1016/j.preteyeres.2021.100967

Figure 2.

Figure 2.

Anti-inflammatory effects of MSCs on the cornea.

Human BM-derived MSCs or vehicle (Hank’s balanced salt solution, HBSS) were administered into mice via tail vein injection immediately after sterile injury to the cornea. Seven days later, the cornea was evaluated clinically for opacity and histologically for neutrophil infiltration. MSCs significantly reduced the development of corneal opacity and neutrophil infiltration.

Reprinted with permission from Cytotherapy. Yun et al., 2017. Comparison of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in a murine model of corneal injury. Cytotherapy 19, 28–35. Copyright © 2017 Elsevier Inc.