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. Author manuscript; available in PMC: 2022 Jun 25.
Published in final edited form as: Circ Res. 2021 Jun 24;129(1):195–215. doi: 10.1161/CIRCRESAHA.121.318174

Figure 6. Imaging Biomarkers of CCM.

Figure 6.

(A). Micro-CT is used to assess lesion burden, volume, and stage ex-vivo in murine brains. (B). Susceptibility weighted MRI assesses lesion burden in familial cases, and the presence of an associated developmental venous anomaly (red arrow) in sporadic cases. (C). Dynamic contrast enhanced quantitative perfusion (DCEQP) MRI assesses the vascular permeability of CCM lesions and background brain. (D). Quantitative susceptibility mapping (QSM) MRI assesses iron content in CCM lesions.