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Effect of DOSPER on antimicrobial activities of antibiotics. A total of 104 CFU of E. coli was cultured in RPMI 1640 (without phenol red or serum) containing graded concentrations of antibiotics with (——) or without (⋯ ⋯) DOSPER (10 μg/ml) in a final volume of 200 μl. Bacterial density was estimated by turbidimetry at 750 nm at 4 h. ●, imipenem; ▴, gentamicin; ■, rifampin; ▾, ceftazidime.
