Table 3.
Statistics for model improvement with the addition of hs‐CRP content
| p‐Value | ||
|---|---|---|
| Events, n (%) | 393 (21.8) | |
| Nonevents, n (%) | 1411 (78.2) | |
| Categorical NRI (%) | ||
| cNRI event | 4.326 | .026 |
| cNRI nonevent | 1.630 | .108 |
| cNRI | 5.956 | .007 |
| IDI statistics | ||
| IDI | 0.0757 (95% CI: 0.0573–0.0942) | <.001 |
| AUC | ||
| Grace risk score | 0.785 (95% CI: 0.758‐0.813) | |
| Grace + hs‐CRP | 0.819 (95% CI: 0.793‐0.845) | |
| Difference | 0.034 | <.001 |
Abbreviations: 95% CI, 95% confidence interval; cNRI, categorical net reclassification improvement; Grace, Global Registry of Acute Coronary Events; hs‐CRP, high‐sensitivity C‐reactive protein; IDI, integrated discrimination improvement; NRI, net reclassification improvement.