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. 2022 Mar 15;15:28. doi: 10.1186/s13068-022-02127-9

Fig. 4.

Fig. 4

Possible strategies to construct robust S. cerevisiae. The response performance of S. cerevisiae to stress factors can be improved with the construction of the tolerant and eliminated pathway in cell. The expression of the single/multiple genes circuit induces the rewriting of the endogenous regulation of S. cerevisiae. Assisting in adaptive evolution to balance the metabolic load of strain can further promote the improvement of S. cerevisiae robustness