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. 2022 Mar 14;22:255. doi: 10.1186/s12879-022-07171-2

Table 1.

Guidelines on testing and treatment of uncomplicated chlamydia (CT) in asymptomatic women and MSM

Testing and treatment^ Urogenital CT Pharyngeal CT Rectal CT
Europe (6), UK (7), Australia (9), US (8) Routine testing (or when a change of sex partner occurs) in people < 25 or 30 years of age and in key populations; implementation in countries varies (e.g., age-based, or by behavioural risk, specific settings/venues) in women and MSM No testing or selective testing based on reports of oral sex or symptoms in women at STI clinics. Several countries recommend routine testing in MSM No testing or selective testing based on reports of anal sex or symptoms in women at STI clinics. Most countries recommend routine testing in MSM
Treatment*
Europe (‘15)# Azithromycin Azithromycin Doxycycline
UK (‘18) Doxycycline Doxycycline Doxycycline
Australia# Doxycycline or Azithromycin Doxycycline or Azithromycin Doxycycline
USA (2021) Doxycycline Doxycycline Doxycycline

^Concerns opportunistic/targeted testing. In addition, in some countries, young people could/can enter community-based testing programs

*Recommended first-line treatment shown

#In the progress of revising guidance