TABLE 4.
Distribution of BARD1 exon genotype in breast cancer group and control group (%)
| Polymorphism | Breast cancer group (N = 60) | Control group (N = 240) | χ 2 | p |
|---|---|---|---|---|
| rs1048108 | ||||
| CC | 24 (40.0%) | 101(42.1%) | — | — |
| CT | 29 (48.3%) | 102 (42.5%) | 0.336 | 0.562 |
| TT | 7 (11.7%) | 37 (15.4%) | 0.235 | 0.628 |
| CT+TT | 36 (60.0%) | 139 (57.9%) | 0.086 | 0.770 |
| rs28997575 | ||||
| Wild‐type | 52 (87.7%) | 230 (95.8%) | — | — |
| Mutation | 8 (13.3%) | 10 (4.2%) | 5.618 | 0.013 |
| rs2229571 | ||||
| GG | 18 (30.0%) | 34 (14.2%) | — | — |
| GC | 25 (41.7%) | 113 (47.0%) | 5.872 | 0.015 |
| CC | 17 (28.3%) | 93 (38.8%) | 7.654 | 0.006 |
| GC+CC | 42 (70.0%) | 206 (85.8%) | 8.398 | 0.004 |
| rs2070094 | ||||
| GG | 36 (60.0%) | 104 (43.3%) | — | — |
| GA | 14 (23.3%) | 107 (44.6%) | 8.384 | 0.004 |
| AA | 10 (16.7%) | 29 (12.1%) | 0.000 | 0.993 |
| GA+AA | 24 (40.0%) | 136 (56.7%) | 5.357 | 0.021 |
| rs3738888 | ||||
| CC | 57 (95.0%) | 231 (96.3%) | — | — |
| CT | 3 (5.0%) | 9 (3.7%) | 0.005 | 0.712 |
The χ² test was used to compare the differences in the frequency of BARD1 genotype loci between patient and control group. Two‐sided test with p < 0.05 was considered statistically significant.