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. 2021 Jul 2;109:203–208. doi: 10.1016/j.ijid.2021.06.063

Table 2.

Association between demographic and clinical variables and long-term sick leave in COVID-19 patients followed in general practices in Germany

Variable Proportion of patients on long-term sick leave (%) OR (95% CI) P value
Total 5.8
Sex
Female 6.5 1.19 (1.07-1.31) <0.001
Male 5.1 Reference
Age (in years)
18–25 2.6 Reference
26–35 2.9 1.10 (0.87-1.39) 0.429
36–45 5.1 1.84 (1.48-2.29) <0.001
46–55 7.5 2.68 (2.17-3.29) <0.001
56–65 10.7 3.71 (3.01-4.58) <0.001
Disorders diagnosed within 12 months prior to the diagnosis of COVID-19a
Noninfective enteritis and colitis 12.3 2.02 (1.70-2.40) <0.001
Reaction to severe stress, and adjustment disorders 11.6 1.68 (1.46-1.92) <0.001
Atopic dermatitis 9.2 1.27 (1.10-1.47) 0.001
Mononeuropathies 11.1 1.27 (1.04-1.57) 0.022
Reflux diseases 11.2 1.24 (1.05-1.47) 0.013
Diabetes mellitus 11.3 1.21 (1.00-1.48) 0.048
Spondylitis 12.3 1.21 (0.99-1.49) 0.063
Hypertension 10.5 1.19 (1.04-1.36) 0.010
Chronic headache 8.2 1.19 (1.00-1.42) 0.056
Phlebitis and thrombosis 11.0 1.17 (0.96-1.42) 0.114
Somatoform disorders 9.9 1.13 (0.96-1.34) 0.132
Sleep disorders 10.1 1.11 (0.94-1.32) 0.218
Chronic sinusitis 7.7 1.11 (0.94-1.32) 0.218
Allergic rhinitis 7.6 1.11 (0.89-1.37) 0.360
Obesity 9.1 1.08 (0.90-1.29) 0.433
Asthma 8.8 1.06 (0.87-1.30) 0.540
Depression 8.6 1.05 (0.91-1.21) 0.506
Gastritis and duodenitis 8.1 1.05 (0.91-1.21) 0.534
Lipid metabolism disorders 9.9 1.04 (0.89-1.21) 0.638
Vitamin D deficiency 8.9 1.03 (0.81-1.31) 0.823
Osteoarthritis 11.2 1.02 (0.87-1.21) 0.784
Cardiac arrhythmias 8.4 1.02 (0.81-1.27) 0.892
Anxiety disorders 8.8 1.02 (0.73-1.15) 0.469
Thyroid gland disorders 8.1 0.99 (0.86-1.14) 0.910

OR: odds ratio.

The adjusted logistic regression model included all demographic and clinical variables displayed in the table.

Long-term sick leave corresponded to sick leave of at least 4 weeks.

a

The reference column corresponds to patients without the disorder of interest.