Table 1.
Virulence factors identified in UPEC-46
| Virulence traits | Virulence factor | Name | Associated with |
|---|---|---|---|
| Adhesion/Invasion | Aap | Dispersin | IPEC |
| Aat | Anti-aggregative transporter1 | IPEC | |
| Csg | Curli1 | Various | |
| IbeB | Invasion protein | ExPEC | |
| IbeC | Invasion protein | ExPEC | |
| NlpI | Lipoprotein | ExPEC | |
| Bacteriocin | ColE1 | Colicin E1 | ExPEC |
| Mcb | Microcin B171 | ExPEC | |
| CU fimbriae | Ecp | E. coli common pilus1 | Various |
| Fim | Type 1 fimbriae1 | Various | |
| Sfm | Sfm fimbriae1 | Various | |
| Yad | Yad fimbriae1 | Various | |
| Ybg | Ybg fimbriae1 | Various | |
| Ycb | Ycb fimbriae1 | Various | |
| Yde | Yde fimbriae1 | Various | |
| Yeh | Yeh fimbriae1 | Various | |
| Yfc | Yfc fimbriae1 | Various | |
| Yhc | Yhc fimbriae1 | Various | |
| Yra | Yra fimbriae1 | Various | |
| Iron uptake | Efe | Efe system1 | Various |
| Ent, Fep | Enterobactin1 | Various | |
| Fec | Ferric citrate transport1 | Various | |
| Feo | Transport of ferrous1 | Various | |
| Fhu | Ferrichrome uptake1 | Various | |
| Ybt, Irp2, Irp1 | Yersiniabactin biosynthetic system1 | Various | |
| FyuA | Yersiniabactin siderophore receptor | ExPEC | |
| Serum resistance | Iss | Serum survival | ExPEC |
| Etk, Etp, Gfc | Group 4 capsule1 | ExPEC | |
| T2SS | Gsp | T2SS-11 | Various |
| T3SS | Eiv, Epa, Epr, Yge | ETT22 | Various |
| T4P | AFP | Aggregate-forming pili1 | IPEC |
| T5SS | AatA | APEC autotransporter | ExPEC |
| Pet | Plasmid-encoded toxin | IPEC | |
| UpaC | UPEC autotransporter C | ExPEC | |
| UpaI | UPEC autotransporter I | ExPEC | |
| EhaC | EHEC autotransporter C | IPEC | |
| T6SS | Aai | AggR-activated island2 | IPEC |
| Toxins | AstA | EAST1 toxin | IPEC |
| HlyE | Hemolysin E | Various |
1, operon complete; 2, operon incomplete; CU, chaperone usher; T2SS, type 2 secretion system; T3SS, type 3 secretion system; T4P, type 4 pili; T5SS, type 5 secretion system; T6SS, type 6 secretion system.