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Antiviral activity of site 1 −1 PRF binders against SARS-CoV-2.
| Analog | Structure | EC50 [μM] | CC50 [μM] |
|---|---|---|---|
| 1 (AB-3234) |
|
13.0 | >100 |
| 2 (AB-3241) |
|
25.2 | >100 |
| 3 (AB-3285) |
|
12.0 | >100 |
EC50 : half-maximal effective concentration, CC50: half-maximal cytotoxic concentration
