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. 2022 Mar 15;66(3):e01702-21. doi: 10.1128/aac.01702-21

FIG 2.

FIG 2

Viral breakthrough of (a) NL4-3 L74, (b) NL4-3 L74I, (c) ConA6 I74L, and (d) ConA6 I74 replication-competent viruses after treatment with no drug or increasing cabotegravir concentrations. The experiment was performed with 6 replicates per virus per treatment. Viral breakthrough was evaluated by visual inspection for syncytia formation. ConA6, consensus A6. aOf 6 replicates. bQ148R resistance mutation emerged in one of 3 breakthrough viruses.