TABLE 1.

Comparison of Baseline Variables Between Those With Coronavirus Disease 2019 and Noncoronavirus Disease 2019 Viral Pneumonias

Clinical Variables	COVID 2019	Non-COVID	p
N	64	49
Age, yr, mean ± sd	45.0 ± 9.4	44.2 ± 11.9	0.71
Sex, female, n (%)	15 (23)	20 (41)	0.048
Body mass index, mean ± sd	28.9 ± 7.0	29.1 ± 7.7	0.93
Hypertension, n (%)	14 (23)	0 (0)	< 0.001
Cardiovascular disease, n (%)	1 (2)	0 (0)	1
Chronic kidney disease, n (%)	1 (2)	0 (0)	1
Diabetes, n (%)	16 (25)	3 (6)	0.01
Preexisting lung disease, n (%)	9 (14)	11 (22)	0.25
Asthma	8 (13)	7 (14)
Other	1 (1)	4 (8)
Viral etiology, n (%)
Severe acute respiratory syndrome coronavirus 2	64 (100)	0
Influenza	0	32 (65)
Respiratory syncytial virus	0	2 (4)
Rhinovirus	0	4 (8)
Coronavirus (non-COVID)	0	2 (4)
Adenovirus	0	3 (6)
Other	0	6 (13)
Vitals at admission to extracorporeal membrane oxygenation, mean ± sd
Heart rate, beats/min	88.8 ± 20.5	91.9 ± 19.3	0.51
Systolic BP, mm Hg	116 ± 20	108 ± 13	0.03
Diastolic BP, mm Hg	68 ± 15	56 ± 7	0.001
Pao2, kPa	12.8 ± 8.9	14.7 ± 7.1	0.34
Baseline biochemical markers
WBC, 109/L	12.9 ± 7.2	11.0 ± 9.1	0.24
Lymphocytes, 109/L	0.85 ± 0.46	0.67 ± 0.56	0.07
Platelet, 109/L	300 ± 120	178 ± 87	< 0.001
C-reactive protein, mg/L	258 ± 130	192 ± 101	0.004
d-dimer, mg/L	13.6 ± 20.0	a
Prothrombin time, s	13.5 ± 2.2	15.4 ± 4.0	0.002
Activated partial thromboplastin time, s	40.2 ± 21.2	50.0 ± 27.9	0.046
Fibrinogen, g/L	7.72 ± 9.94	4.09 ± 2.59	0.01
Urea, mmol/L	14.7 ± 9.9	11.3 ± 7.0	0.04
Creatinine, μmol/L	177 ± 190	154 ± 104	0.42
Acute Physiology and Chronic Health Evaluation score	13.9 ± 6.1	14.4 ± 4.1	0.70

BP = blood pressure, COVID = coronavirus disease.

^ad-dimer was not routinely collected in extracorporeal membrane oxygenation admission bloods pre COVID.