Table 3.
Comparison of cytologic features between groups 1 and 2
| Cytologic features | Group 1 (n=36) | Group 2 (n=38) | Total | P | Test performed |
|---|---|---|---|---|---|
| Papillae with cores | |||||
| Absent | 14 (38.89%) | 32 (84.21%) | 46 (62.16%) | <0.0001 | Chi-square test, 16.144 |
| Present | 22 (61.11%) | 6 (15.79%) | 28 (37.84%) | ||
| 3D caps | |||||
| Absent | 18 (50%) | 34 (89.47%) | 52 (70.27%) | 0.0003 | Fisher’s Exact test |
| Present | 18 (50%) | 4 (10.53%) | 22 (29.73%) | ||
| Cellular swirls | |||||
| Absent | 17 (47.22%) | 38 (100%) | 55 (74.3%) | <0.0001 | Fisher’s Exact test |
| Present | 19 (52.78%) | 0 (0%) | 19 (25.6%) | ||
| Colloid | |||||
| Absent | 10 (27.78%) | 3 (7.89%) | 13 (17.57%) | 0.0002 | Fisher’s Exact test |
| Thick | 16 (44.44%) | 6 (15.79%) | 22 (29.73%) | ||
| Thick and thin | 0 (0%) | 4 (10.53%) | 4 (5.41%) | ||
| Thin | 10 (27.78%) | 25 (65.79%) | 35 (47.30%) | ||
| Giant cells | |||||
| Absent | 16 (44.44%) | 26 (68.42%) | 42 (56.76%) | 0.037 | Chi-square test, 4.33 |
| Present | 20 (55.56%) | 12 (31.58%) | 32 (43.24%) | ||
| Cyst macrophages | |||||
| Absent | 16 (44.44%) | 11 (28.95%) | 27 (36.49%) | 0.166 | Chi square test, 1.916 |
| Present | 20 (55.56%) | 27 (71.05%) | 47 (63.51%) | ||
| Nuclear grooves | |||||
| Many/frequent throughout the smear | 22 (61.11%) | 1 (2.63%) | 23 (31.08%) | <0.0001 | Chi-square test, 40.873 |
| Frequent in occasional groups of cells | 7 (19.44%) | 4 (10.53%) | 11 (14.86%) | ||
| Occasional throughout the smear | 5 (13.89%) | 7 (18.42%) | 12 (16.22%) | ||
| Absent | 2 (5.56%) | 26 (68.42%) | 28 (37.84%) | ||
| Nuclear grooves (present/absent) | |||||
| Absent | 2 (5.56%) | 26 (68.42%) | 28 (37.84%) | <0.0001 | Fisher’s Exact test |
| Present | 34 (94.44%) | 12 (31.58%) | 46 (62.16%) | ||
| Frequent Nuclear grooves (positive/negative) | |||||
| Negative | 14 (38.89%) | 37 (97.37%) | 51 (68.92%) | <0.0001 | Fisher’s Exact test |
| Positive | 22 (61.11%) | 1 (2.63%) | 23 (31.08%) | ||
| Intra-nuclear cytoplasmic inclusion | |||||
| Many/frequent throughout the smear | 11 (30.56%) | 0 (0%) | 11 (14.86%) | <0.0001 | Fisher’s Exact test |
| Frequent in occasional groups of cells | 8 (22.22%) | 0 (0%) | 8 (10.81%) | ||
| Occasional throughout the smear | 4 (11.11%) | 2 (5.26%) | 6 (8.10%) | ||
| Absent | 13 (36.11%) | 36 (94.73%) | 49 (63.51%) | ||
| Intra-nuclear cytoplasmic inclusion (present/absent) | |||||
| Absent | 13 (36.11%) | 36 (94.73%) | 49 (66.21%) | <0.0001 | Fisher’s Exact test |
| Present | 23 (63.89%) | 2 (5.26%) | 25 (33.78%) | ||
| Frequent Intra-nuclear cytoplasmic inclusion (positive/negative) | |||||
| Negative | 25 (69.44%) | 38 (100%) | 63 (85.14%) | 0.0001 | Fisher’s Exact test |
| Positive | 11 (30.56%) | 0 (0%) | 11 (14.86%) | ||
| Powdery chromatin | |||||
| Absent | 16 (44.44%) | 30 (78.95%) | 46 (62.16%) | 0.002 | Chi-square test, 9.357 |
| Present | 20 (55.56%) | 8 (21.05%) | 28 (37.84%) | ||
| Psammoma body | |||||
| Absent | 31 (86.11%) | 37 (97.37%) | 68 (91.89%) | 0.103 | Fisher’s Exact test |
| Present | 5 (13.89%) | 1 (2.63%) | 6 (8.11%) | ||
| Nuclear overlapping | |||||
| Absent | 10 (27.78%) | 18 (47.37%) | 28 (37.84%) | 0.082 | Chi-square test, 3.016 |
| Present | 26 (72.22%) | 20 (52.63%) | 46 (62.16%) | ||
| Cytoplasmic Vacuoles | |||||
| Absent | 26 (72.22%) | 35 (92.11%) | 61 (82.43%) | 0.033 | Fisher’s Exact test |
| Present | 10 (27.78%) | 3 (7.89%) | 13 (17.57%) | ||
| Squamous Metaplastic cells | |||||
| Absent | 18 (50%) | 31 (81.58%) | 49 (66.22%) | 0.004 | Chi-square test, 8.241 |
| Present | 18 (50%) | 7 (18.42%) | 25 (33.78%) | ||
| Nuclear atypia/enlargement | |||||
| Present | 25 (69.44%) | 8 (21.05%) | 27 (36.49%) | 0.020 | Chi-square test, 5.3667 |
| Absent | 11 (30.5.%) | 30 (31.58%) | 12 (16.22%) | ||
| Number of nuclei in giant cells | |||||
| Mean±SD | 10.25±15.14 | 3.32±5.28 | 6.69±11.67 | 0.039 | Mann-Whitney test; 510.5 |
| Median (IQR) | 4.5 (0-11.25) | 0 (0-7.25) | 0 (0-10) | ||
| Range | 0-55 | 0-20 | 0-55 |