Table 2.
The chi-square analysis of the connection between F–SII and clinicopathological features in Groups A and B.
| Characteristics | Group A | Group B | ||||||
|---|---|---|---|---|---|---|---|---|
| F–SII = 0 (n = 137) | F–SII = 1 (n = 121) | F–SII = 2 (n = 57) | P value | F–SII = 0 (n = 236) | F–SII = 1 (n = 148) | F–SII = 2 (n = 56) | P value | |
| Sex | 0.420 | 0.120 | ||||||
| Male | 99 (41.6) | 93 (39.1) | 46 (19.3) | 187 (55.8) | 104 (31.0) | 44 (13.1) | ||
| Female | 38 (49.4) | 28 (36.4) | 11 (14.3) | 49 (46.7) | 44 (41.9) | 12 (11.4) | ||
| Age (years) | 0.224 | 0.024 | ||||||
| ≤60 | 76 (47.5) | 60 (37.5) | 24 (15.0) | 150 (58.4) | 82 (31.9) | 25 (9.7) | ||
| >60 | 61 (39.4) | 61 (39.4) | 33 (21.3) | 86 (47.0) | 66 (36.1) | 31 (16.9) | ||
| BMI | 0.133 | 0.083 | ||||||
| ≤21.92 | 72 (49.7) | 46 (31.7) | 27 (18.6) | 81 (48.2) | 59 (35.1) | 28 (16.7) | ||
| >21.92 | 48 (40.3) | 52 (43.7) | 19 (16.0) | 155 (57.0) | 89 (32.7) | 28 (10.3) | ||
| Borrmann type | 0.145 | 0.042 | ||||||
| 0 | 14 (70.0) | 5 (25.0) | 1 (5.0) | 43 (71.7) | 16 (26.7) | 1 (1.7) | ||
| 1 | 6 (42.9) | 5 (35.7) | 3 (21.4) | 15 (65.2) | 7 (30.4) | 1 (4.3) | ||
| 2 | 36 (48.0) | 25 (33.3) | 14 (18.7) | 62 (48.4) | 46 (35.9) | 20 (15.6) | ||
| 3 | 79 (40.7) | 78 (40.2) | 37 (19.1) | 108 (51.4) | 72 (34.3) | 30 (14.3) | ||
| 4 | 2 (16.7) | 8 (66.7) | 2 (16.7) | 8 (42.1) | 7 (36.8) | 4 (21.1) | ||
| Tumor location | 0.639 | 0.189 | ||||||
| Upper third | 13 (41.9) | 14 (45.2) | 4 (12.9) | 20 (43.5) | 20 (43.5) | 6 (13.0) | ||
| Middle third | 24 (42.1) | 25 (43.9) | 8 (14.0) | 23 (43.4) | 23 (43.4) | 7 (13.2) | ||
| Lower and entire third | 100 (44.1) | 82 (36.1) | 45 (19.8) | 193 (56.6) | 105 (30.8) | 43 (12.6) | ||
| Tumor diameter (mm) | ＜0.001 | ＜0.001 | ||||||
| ≤50 | 119 (51.3) | 73 (31.5) | 40 (17.2) | 205 (60.8) | 101 (30.0) | 31 (9.2) | ||
| >50 | 18 (21.7) | 48 (57.8) | 17 (20.5) | 31 (30.1) | 47 (45.6) | 25 (24.3) | ||
| Scope of gastrectomy | 0.739 | 0.151 | ||||||
| Proximal gastrectomy | 12 (44.4) | 11 (40.7) | 4 (14.8) | 18 (46.2) | 15 (38.5) | 6 (15.4) | ||
| Distal gastrectomy | 105 (45.3) | 85 (36.6) | 42 (18.1) | 194 (56.7) | 106 (31.0) | 42 (12.3) | ||
| Total gastrectomy | 20 (35.7) | 25 (44.6) | 11 (19.6) | 24 (40.7) | 27 (45.8) | 8 (13.6) | ||
| Lymph node metastasis rate (%) | 0.072 | 0.790 | ||||||
| 0 | 69 (45.1) | 56 (36.6) | 28 (18.3) | 176 (54.0) | 111 (34.0) | 39 (12.0) | ||
| >0 to ≤0.3 | 55 (48.2) | 38 (33.3) | 21 (18.4) | 58 (53.7) | 34 (31.5) | 16 (14.8) | ||
| >0.3 to ≤1 | 13 (27.1) | 27 (56.3) | 8 (16.7) | 2 (33.3) | 3 (50.0) | 1 (16.7) | ||
| pTNM stagea | 0.002 | ＜0.001 | ||||||
| I | 53 (58.2) | 29 (31.9) | 9 (9.9) | 117 (73.1) | 38 (23.8) | 5 (3.1) | ||
| II | 40 (38.8) | 36 (35.0) | 27 (26.2) | 119 (42.5) | 110 (39.3) | 51 (18.2) | ||
| III | 44 (36.4) | 56 (46.3) | 21 (17.4) | - | - | - | ||
| Histological type | 0.320 | 0.966 | ||||||
| Well and moderately differentiated | 56 (46.3) | 43 (35.5) | 22 (18.2) | 110 (52.9) | 70 (33.7) | 28 (13.5) | ||
| Poorly differentiated | 73 (43.5) | 63 (37.5) | 32 (19.0) | 97 (53.9) | 60 (33.3) | 23 (12.8) | ||
| Others | 8 (30.8) | 15 (57.7) | 3 (11.5) | 29 (55.8) | 18 (34.6) | 5 (9.6) | ||
| H. pylori infection | 0.983 | 0.781 | ||||||
| Negative | 17 (39.5) | 15 (34.9) | 11 (25.6) | 20 (43.5) | 17 (37.0) | 9 (19.6) | ||
| Positive | 23 (38.3) | 22 (36.7) | 15 (25.0) | 36 (50.0) | 23 (31.9) | 13 (18.1) | ||
SII: systemic immune inflammation index, F: fibrinogen. aBased on the eighth edition of the AJCC Cancer Staging Manual of the American Joint Committee on Cancer. Statistically significant P values are in bold (P < 0.05).