Table 3.
Prognosis factors of patients in Groups A and B by univariate and multivariate cox regression analysis.
| Characteristics | Group A | Group B | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
| Or (95% CI) | P value | Or (95% CI) | P value | Or (95% CI) | P value | Or (95% CI) | P value | |
| Sex | 0.073 | — | — | 0.445 | — | — | ||
| Male | 1 | 1 | ||||||
| Female | 2.009 (0.938–4.305) | 1.263 (0.694–2.300) | ||||||
| Age (years) | 1.034 (1.004–1.066) | 0.027 | 1.022 (0.989–1.056) | 0.196 | 1.069 (1.040–1.098) | ＜0.001 | 1.070 (1.037–1.105) | ＜0.001 |
| Fibrinogen | 1.909 (1.336–2.728) | ＜0.001 | 1.547 (1.041–2.300) | 0.031 | 1.556 (1.201–2.017) | 0.001 | 1.268 (1.042–1.544) | 0.018 |
| SII | 1.001 (1.000–1.002) | 0.002 | 1.001 (1.000–1.002) | 0.039 | 1.003 (1.002–1.004) | ＜0.001 | 1.003 (1.002–1.004) | ＜0.001 |
| BMI | 0.958 (0.866–1.061) | 0.412 | — | — | 0.897 (0.822–0.980) | 0.016 | 0.911 (0.821–1.009) | 0.075 |
| Borrmann type | 0.897 | — | — | 0.014 | 0.165 | |||
| 0 | 1 | 1 | 1 | |||||
| 1 | 0.667 (0.104–4.261) | 0.668 | 5.619 (0.484–65.218) | 0.168 | 2.806 (0.188–41.846) | 0.454 | ||
| 2 | 1.000 (0.291–3.432) | 1.000 | 11.579 (1.519–88.265) | 0.018 | 6.647 (0.742–59.542) | 0.090 | ||
| 3 | 0.943 (0.298–2.985) | 0.920 | 17.481 (2.360–129.505) | 0.005 | 9.346 (1.074–81.364) | 0.043 | ||
| 4 | 0.364 (0.036–3.707) | 0.393 | 27.231 (3.016–245.887) | 0.003 | 12.220 (1.014–147.266) | 0.049 | ||
| Tumor location | 0.342 | — | — | ＜0.001 | 0.844 | |||
| Lower and entire third | 1 | 1 | 1 | |||||
| Middle third | 1.619 (0.807–3.250) | 0.175 | 2.705 (1.395–5.246) | 0.003 | 1.148 (0.447–2.952) | 0.774 | ||
| Upper third | 1.451 (0.583–3.608) | 0.424 | 3.027 (1.520–6.029) | 0.002 | 0.817 (0.227–2.949) | 0.758 | ||
| Tumor diameter (mm) | 1.025 (1.011–1.039) | 0.001 | 1.009 (0.993–1.026) | 0.281 | 1.023 (1.012–1034) | ＜0.001 | 0.996 (0.981–1.012) | 0.641 |
| Scope of gastrectomy | 0.051 | 0.547 | ＜0.001 | 0.035 | ||||
| Distal gastrectomy | 1 | 1 | 1 | 1 | ||||
| Proximal gastrectomy | 0.435 (0.223–0.850) | 0.015 | 1.524 (0.503–4.618) | 0.457 | 4.711 (2.311–9.605) | ＜0.001 | 4.846 (1.277–18.394) | 0.020 |
| Total gastrectomy | 0.521 (0.169–1.607) | 0.257 | 1.435 (0.658–3.130) | 0.363 | 2.973 (1.571–5.629) | 0.001 | 2.868 (1.114–7.383) | 0.029 |
| Lymph node metastasis rate (%) | 3.871 (0.872–17.182) | 0.075 | — | — | 15.462 (0.938–254.878) | 0.055 | — | — |
| pTNM stage | ＜0.001 | 0.019 | ＜0.001 | 0.169 | ||||
| I | 1 | 1 | 1 | 1 | ||||
| II | 5.570 (1.834–16.918) | 0.002 | 3.530 (1.117–11.156) | 0.032 | 5.487 (2.656–11.332) | 1.833 (0.774–4.344) | ||
| III | 8.500 (2.893–24.975) | ＜0.001 | 5.161 (1.642–16.225) | 0.005 | — | — | — | — |
| Histological type | 0.764 | — | — | 0.221 | — | — | ||
| Well and moderately differentiated | 1 | 1 | ||||||
| Poorly differentiated | 1.094 (0.375–3.189) | 0.870 | 1.588 (0.937–2.690) | 0.086 | ||||
| Others | 0.876 (0.305–2.515) | 0.806 | 1.413 (0.641–3.115) | 0.392 | ||||
| H. pylori infection | 1.058 (0.433–2.583) | 0.902 | — | — | 0.672 (0.301–1.499) | 0.331 | — | — |
aBased on the eighth edition of the AJCC Cancer Staging Manual of the American Joint Committee on Cancer. Statistically significant P values are in bold (P < 0.05).