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CircRHOT1 contributes to the proliferation of chondrocytes by targeting the miR-142-5p/CCND1 axis. (a)–(e) The chondrocytes were treated with circRHOT1 shRNA or cotreated with circRHOT1 shRNA and CCND1 overexpressing plasmid or miR-142-5p inhibitor. (a) The cell viability was detected by CCK-8 assays. (b, c) The cell proliferation was analyzed by colony formation assays. Magnification, ×20. (d, e) The cell apoptosis was assessed by FACS flow cytometer. Mean ± SD, ∗∗P < 0.01.
