Table 1.
Change in Mean Best Corrected Visual Acuity, CMT and VM Relative to Baseline
| Baseline (n=46) Mean ± SD | 6 Months (n= 36) | p value CI | 12 Months (n= 34) | p value CI | 24 Months (n = 28) | p value CI | |
|---|---|---|---|---|---|---|---|
| ETDRS (score letters) | 53.3 ± 14.7 | ||||||
| Visual gain (letters) | +4.6 | 0.002 [1.8; 7.4] | +6 | 0.007 [0; 11.4] | +5.4 | 0.01 [1.3; 9.5] | |
| CMT (µm) | 430 ± 143 | ||||||
| Reduction of CMT (µm) | −64.7 | 0.003 [−106.8; −22.7] | −54 | <0.001 [−100;-29] | −62 | <0.001 [−118; −38.5] | |
| Macula volume (mm3) | 10.1 ± 2.5 | ||||||
| Reduction of Macular Volume | −0.9 | 0.001 [−1.4; −0.4] | 0.001 [−1.6; −0.4] | −1 | 0.03 [−1.6; −0.4] |
Abbreviations: ETDRS, Early Treatment Diabetic Retinopathy Study (ETDRS); CMT, central Macular thickness; VM, macular volume; CI, Confidence Interval.