Figure 2.

fALFF analysis among the 4 groups. (A) One-way ANOVA analysis on fALFF among the 4 groups. (B) Two-sample t-test on fALFF between M+/D− and M−/D−. On the right, the histograms exhibit the mean fALFF value by group (error bars represent standard error from the mean) in each identified ROI. *, P<0.05 (Bonferroni corrected). M+/D+: patients with comorbid migraine and depression; M+/D−: patients with migraine; M−/D+: patients with major depressive disorder; M−/D−: healthy controls. fALFF, fractional amplitude of low-frequency fluctuations; ROI, region of interest; L, left; ANOVA, analysis of variance.