Fig. 3.

ROC of models from the discovery cohort. (A) Overall comparison. Note that the clinical+MRI model is superior to clinical model (AUC 0.843 vs. 0.707, p<0.0001). (B) Components of the clinical+MRI model, compared to the full model. (C) Comparison of the clinical+MRI model to MRI+PSA density and MRI score alone. Clinical+MRI is superior to both MRI+PSA density (AUC 0.843 vs. 0.796, p<0.0001) and MRI alone models (AUC 0.843 vs. 0.760, p<0.0001). AUC: area under the curve; DRE: digital rectal exam; MRI: magnetic resonance imaging; PSA: prostate-specific antigen; ROC: receiver operating characteristic.