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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Microvasc Res. 2022 Feb 7;141:104337. doi: 10.1016/j.mvr.2022.104337

Table 5:

Cell repair & genome stability enriched pathways for NRF1 and ID3 target genes

GO ID GO Description p-value Genes
6281 DNA Repair 0.000000008 MDC1, DCLRE1C, MPG, CCNH, MUM1, NUDT1, SMC6, SMC3, EME1, PTTG1, KAT5, EME2, CDH1, FBXO6, EPC2, NBN, FBXO18, USP3, NSMCE2, RECQL, REV1, LIG4, SETMAR, WRNIP1, CSNK1D, ESCO2, RBX1, MSH6, NEIL2, MSH2, POLG2, FANCD2, UBE2V2, DNA2, NEIL1, ASF1A, VCP, XPA, XPC, BRCC3, RAD51AP1, BRIP1, NTHL1, TP53BP1, CLSPN, FANCI, BARD1, UVRAG, XRCC6, UBE2B, XRCC4, FANCL, XRCC5, GADD45A, INTS3, XRCC2, XRCC3, FANCA, FANCC, UBE2A, FANCE, FANCF, GADD45G, TDP2, TDP1, JMY, UBE2N, ATM, RAD18, TP73, ATR, BTG2, SMG1, FEN1, OGG1, CEP164, HMGB2, POLB, CHAF1A, EXO1, UIMC1, REV3L, POLL, POLK, POLH, POLG, PARP3, RBM14, PARP4, RFC4, RFC1, RFC2, RAD23A, KIF22, SMC1A, SENP2, BAZ1B, SIRT1, DDB2, RNF168, RAD51B, KIN, SFPQ, RRM2B, PAPD7, CRY2, CRY1, DTL, FAN1, USP10, PNKP, RNF8, TYMS, FZR1, WRN, SLX4, POLD2, PMS2, RAD54L, ZSWIM7, PMS1, MUTYH, MBD4, EYA1, EYA3, RPA1, APEX2, MRE11A, RPA2, GTF2H1, MLH1, USP28, APTX, GTF2H5, TICRR, HINFP, RAD52, EEPD1, XAB2, RAD51, ERCC3, POLE2, RFWD3, RPA3, APLF, ERCC2, ERCC6, TRIP13
6289 nucleotide-excision repair 0.039448 CCNH, PNKP, OGG1, XPA, XPC, SLX4, NTHL1, POLD2, POLL, RFC4, RFC1, RFC2, RPA1, LIG4, RPA2, FANCC, RAD23A, GTF2H1, GTF2H5, DDB2, XAB2, NEIL2, ERCC3, POLE2, RPA3, ERCC2, ERCC6, NEIL1, FAN1
6302 Double-strand break repair 0.00007 VCP, FEN1, DCLRE1C, RNF8, BRCC3, RAD51AP1, BRIP1, SLX4, KAT5, UIMC1, RAD54L, NBN, POLK, XRCC6, EYA1, XRCC4, XRCC5, EYA3, XRCC2, RECQL, RPA1, MRE11A, LIG4, MLH1, BAZ1B, APTX, RNF168, RAD52, RAD51, MSH2, PAPD7, TDP2, TDP1, APLF, UBE2V2, UBE2N, TRIP13, FAN1