Table 3.
Results of the multivariable cox proportional hazard regression model evaluating the adjusted association between clinical/sociodemographic characteristics at presentation with mortality over the course of the study. HR – hazard ratio; CI – confidence interval; Ref – referent
| Characteristics | HR | 95% CI | p-value |
|---|---|---|---|
| New England Spinal Metastases Score | |||
| 0 | 5.61 | 2.83, 11.13 | <0.001 |
| 1 | 3.00 | 1.60, 5.63 | 0.001 |
| 2 | 1.67 | 0.94, 2.97 | 0.08 |
| 3 | Ref | Ref | Ref |
| Male Sex | 1.18 | 0.80, 1.73 | 0.40 |
| Neurologic Deficits at Presentation | 1.39 | 0.87, 2.21 | 0.16 |
| Number of Co-morbidities | 1.01 | 0.80, 1.27 | 0.91 |
| Treatment Strategy | |||
| Non-operative | Ref | Ref | Ref |
| Operative | 0.68 | 0.44, 1.06 | 0.09 |
| Lytic Metastases | 0.92 | 0.62, 1.37 | 0.68 |
| Age | |||
| 50 or younger | Ref | Ref | Ref |
| 51-60 | 0.73 | 0.41, 1.30 | 0.29 |
| 61-70 | 0.52 | 0.29, 0.93 | 0.03 |
| 71 or older | 0.85 | 0.44, 1.63 | 0.63 |
| Vertebral Body Collapse | |||
| No collapse with <50% involvement | Ref | Ref | Ref |
| No collapse with ≥50% involvement | 1.07 | 0.57, 2.00 | 0.84 |
| Collapse with <50% involvement | 1.01 | 0.54, 1.86 | 0.99 |
| Collapse with ≥50% involvement | 0.66 | 0.34, 1.26 | 0.21 |
| Vertebral Body Metastases | |||
| 1 | Ref | Ref | Ref |
| 2 | 0.97 | 0.49, 1.93 | 0.93 |
| 3 or more | 0.89 | 0.49, 1.64 | 0.72 |