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. 2022 Mar 15;8:117. doi: 10.1038/s41420-022-00923-8

Fig. 1. The expression of c-Myc is negatively correlated with T-cell infiltration in many solid tumors.

Fig. 1

A Analysis of the correlation between c-Myc expression and CD45, CD4, CD8 expression in LUSC, SKCM, HNSC, UVM, AML, and LGG (TCGA dataset). B Correlation between c-Myc expression and immune cell marker expression in osteosarcoma (GEO dataset, GSE33382). C The relationship between the expression of c-Myc, CD4, CD8, CD19, CD80, F4/80, and the prognosis of osteosarcoma (TARGET database). D Representative pictures of immunohistochemical staining of c-Myc, CD4, and CD8 in 80 human osteosarcoma samples. scale bar: 100 μm. Statistical comparisons were performed using Fisher’s exact test (E).