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. 2022 Mar 15;8:117. doi: 10.1038/s41420-022-00923-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Representative immunofluorescence staining of CD40 and CD40L in K7M2 tumors (400×, scale bar: 100 μm). B, C Representative bioluminescence of K7M2 model at day 28 post first treatment, tumor burdens were evaluated by total flux. D The long-term survival of mice treated with DMSO, JQ-1, or JQ-1 plus CD40L block antibody is shown. E, F The proportion of CD44 + CD62L-populations in CD4+ T cells or CD8+ T cells.