Table 2.

Factors associated with myocardial involvement in children with MIS-C.

Parameter	Se	Sp	OR (95% CI)	p
D-dimer >1,300, ng/ml	84.8	63	9.6 (3.1; 29.4)	0.00002
Ferritin >241.0, μg/L	77.1	60.4	5.2 (1.9; 13.7)	0.0007
Hscore >135	47.4	90.3	8.4 (2.9; 24.1)	0.00002
Total protein ≤ 46.1, g/L	35.9	95.9	13.2 (2.8; 62.6)	0.0001
Troponin >31.6, pg/ml	51.9	100.0	-	0.0002
Respiratory signs	59.2	60.0	2.2 (0.98; 4.8)	0.052
Gastrointestinal symptoms	30.0	85.0	2.4 (0.9; 6.7)	0.079
Sore throat	42.0	77.5	2.5 (1.03; 6.0)	0.039
Cervical lymphadenopathy	29.0	88.9	3.3 (1.02; 10.4)	0.038
Hands/feet erythema/edema	42.6	82.9	3.6 (1.3; 9.8)	0.010
Face swelling	60.6	73.0	4.2 (1.7; 10.0)	0.001
Splenomegaly	73.8	62.5	4.7 (2.0; 11.0	0.0002
Shock/hypotension	65.3	65.0	3.5 (1.6; 7.9)	0.002
ICU admission	65.3	75.0	5.7 (2.4; 13.4)	0.00001
MAS 2005	69.4	52.6	2.5 (1.1; 5.8)	0.029

Se, sensitivity; Sp, specificity; OR, odds ratio; CI, confidence interval; ICU, intensive care unit; MAS, macrophage activation syndrome.