TABLE 1.
Comparison of DTI metrics of FA and MD in NAWM tracts between RRMS patients and controls using two-tailed Student’s t-test.
| Location | Side | FA (mean ± SD) |
MD (mean ± SD) 10–3 mm2 s–1 |
||
| RRMS | Control | RRMS | Control | ||
| SCR | Left | 0.3816 ± 0.0375 | 0.4307 ± 0.0577 | 0.7769 ± 0.0664** | 0.6785 ± 0.0199 |
| SCR | Right | 0.3918 ± 0.0331 | 0.4824 ± 0.0450 | 0.7976 ± 0.0731** | 0.6954 ± 0.0429 |
| SLF | Left | 0.3418 ± 0.0221 | 0.3769 ± 0.0386 | 0.8127 ± 0.0618 | 0.7523 ± 0.0380 |
| SLF | Right | 0.3377 ± 0.0352 | 0.3871 ± 0.0458 | 0.8106 ± 0.0510 | 0.7611 ± 0.0333 |
| ACR | Left | 0.3425 ± 0.0400** | 0.3975 ± 0.0200 | 0.8397 ± 0.0716** | 0.7418 ± 0.0226 |
| ACR | Right | 0.3390 ± 0.0393** | 0.4034 ± 0.0292 | 0.7403 ± 0.0817** | 0.8474 ± 0.0279 |
| BCC | – | 0.3831 ± 0.0389** | 0.4503 ± 0.0334 | 1.0156 ± 0.1421 | 0.9606 ± 0.1271 |
| CIN | Left | 0.2707 ± 0.0423 | 0.3045 ± 0.0514 | 0.8690 ± 0.0659 | 0.8140 ± 0.0377 |
| CIN | Right | 0.2642 ± 0.0381 | 0.0304 ± 0.0460 | 0.8361 ± 0.0586 | 0.7950 ± 0.0510 |
| EC | Left | 0.3295 ± 0.0221 | 0.3423 ± 0.0205 | 0.8242 ± 0.0569 | 0.7698 ± 0.0392 |
| EC | Right | 0.3294 ± 0.0213 | 0.3331 ± 0.0191 | 0.8322 ± 0.0504 | 0.7775 ± 0.0243 |
| GCC | – | 0.3549 ± 0.0423** | 0.4227 ± 0.0369 | 1.1287 ± 0.0906 | 1.0199 ± 0.0898 |
| PTR | Left | 0.4035 ± 0.0614 | 0.4472 ± 0.0318 | 0.945 ± 0.1245 | 0.8181 ± 0.0534 |
| PTR | Right | 0.3930 ± 0.0508* | 0.4534 ± 0.0266 | 0.8538 ± 0.0974 | 0.7432 ± 0.0832 |
| SCC | – | 0.4159 ± 0.0464** | 0.5087 ± 0.0393 | 1.1251 ± 0.1456 | 1.0363 ± 0.0937 |
| TAP | Left | 0.3685 ± 0.0540 | 0.3703 ± 0.0965 | 1.2971 ± 0.2899 | 1.5991 ± 0.3597 |
Significant differences of FA and MD between RRMS patients and healthy controls are shown by FDR adjusted *p < 0.01 and highly significant differences by **p < 0.001.