Table 3.
Survival comparison of molecular subtypes determined by immunohistochemical staining in primary small cell lung cancer tumors.
| Survival Outcome | ASCL1-subtype | NEUROD1-subtype | POU2F3-subtype | YAP1-subtype | P value |
|---|---|---|---|---|---|
| Overall survival | 0.007 | ||||
| Median(months) | 37.7 | 29.5 | — | — | |
| 1-year(%) | 86.4 | 80.3 | 89.3 | — | |
| 3-year(%) | 50.1 | — | 68.9 | 82.4 | |
| 5-year(%) | 34.7 | — | — | — | |
| Disease-free survival | 0.000 | ||||
| Median(months) | 16.9 | 20.0 | — | — | |
| 1-year(%) | 61.1 | 67.8 | 83.3 | 95.7 | |
| 2-year(%) | 38.3 | — | — | 80.6 | |
| 3-year(%) | 28.0 | — | 61.3 | — |
ASCL1, achaete-scute homologue 1; NEUROD1, neurogenic differentiation factor 1; POU2F3, POU class 2 homeobox 3; YAP1, yes-associated protein 1.