TABLE 1.

Di- and trihydroxylated oxylipins derived from AA, EPA and DHA.

Hydroxylation	Trivial name	Hydroxylation pattern	Proposed pathway of formation
dihydroxy derivatives	5,15-diHETE	5,15-diHETE a	12/15-LO:5-LO, 5-LO:12/15-LO
	8,15-diHETE	8,15-diHETE	12/15-LO
	resolvin D5	7,17-diHDHAb	12/15-LO:5-LO
	resolvin D6	4,17-diHDHA	12/15-LO:5-LO
	resolvin E2	5,18-diHEPE c	CYP or (12/15LO):5-LO
	resolvin E3	17,18-diHEPE	CYP, (12/15-LO)
	resolvin E4	5,15-diHEPE	12/15-LO:5-LO, 5-LO:12/15-LO
trihydroxy derivatives	lipoxin A4	5,6,15-triHETE	5-LO:12/15-LO
	lipoxin B4	5,14,15-triHETE	5-LO:12/15-LO
	resolvin D1	7,8,17-triHDHA	12/15-LO:5-LO
	resolvin D2	7,16,17-triHDHA	12/15-LO:5-LO
	resolvin D3	4,11,17-triHDHA	12/15-LO:5-LO
	resolvin D4	4,5,17-triHDHA	12/15-LO:5-LO
	resolvin E1	5,12,18-triHEPE	CYP or (12/15-LO):5-LO

^aHydroxyeicosatetraenoic acid.

^bHydroxydocosahexaenoic acid.

^cHydroxyeicosapentaenoic acid.