Table 3. Multiple Logistic Regression of Characteristics of Patients With ICH Comparing Odds of Neurologic Disability or Mortality After ICHa.
Variable | Estimate (SE) | Odds ratio (95% CI) | P value |
---|---|---|---|
Log of ICH volume | 1.01 (0.08) | 2.74 (2.36-3.19) | <.001 |
ICH location | |||
Brainstem | 1.39 (0.28) | 4.03 (2.34-6.95) | <.001 |
Cerebellum | −0.53 (0.24) | 0.59 (0.37-0.94) | .03 |
Deep | NA | 1 [Reference] | NA |
Lobar | −1.53 (0.17) | 0.22 (0.16-0.30) | <.001 |
Prestroke mRS score | 0.48 (0.07) | 1.62 (1.41-1.87) | <.001 |
Admission GCS score | −0.12 (0.02) | 0.88 (0.85-0.92) | <.001 |
Age, per 1-y increase | 0.04 (0.006) | 1.04 (1.02-1.05) | <.001 |
Presence of infection | 0.62 (0.13) | 1.85 (1.42-2.41) | <.001 |
Hematoma expansion | 0.79 (0.18) | 2.20 (1.55-3.13) | <.001 |
Treatment required | |||
ICP treatment | 0.74 (0.18) | 2.09 (1.46-3.00) | <.001 |
Tracheostomy | 1.84 (0.52) | 6.31 (2.29-17.35) | <.001 |
Intraventricular drain | 0.64 (0.19) | 1.89 (1.30-2.74) | <.001 |
Total Graeb score | 0.11 (0.03) | 1.12 (1.05-1.18) | <.001 |
Female sex | 0.43 (0.13) | 1.53 (1.19-1.98) | .001 |
Prior use of α-2 adrenergic | 0.81 (0.27) | 2.24 (1.32-3.82) | .003 |
Total van Swieten score | 0.14 (0.05) | 1.15 (1.04-1.26) | .005 |
Medical history | |||
Alzheimer or dementia | 0.92 (0.30) | 2.51 (1.40-4.51) | .002 |
Migraine | −0.97 (0.38) | 0.38 (0.18-0.80) | .01 |
Ischemic stroke | 0.48 (0.20) | 1.62 (1.11-2.37) | .01 |
Diabetes | 0.34 (0.14) | 1.40 (1.07-1.83) | .01 |
Cardiomyopathy | 0.77 (0.35) | 2.15 (1.08-4.27) | .03 |
ICH | 0.46 (0.27) | 1.59 (0.94-2.68) | .08 |
Hypertension | 0.22 (0.18) | 1.24 (0.88-1.75) | .22 |
Total atrophy score | 0.15 (0.06) | 1.16 (1.03-1.31) | .02 |
APOE 2 allele | 0.36 (0.17) | 1.43 (1.02-2.01) | .04 |
Clinical seizure | 0.45 (0.23) | 1.56 (1.00-2.43) | .05 |
Prior use of anticoagulants | −0.24 (0.20) | 0.79 (0.53-1.16) | .23 |
Abbreviations: GCS, Glasgow Coma Scale; ICH, intracerebral hemorrhage; ICP, intracranial pressure; mRS, modified Rankin Scale; NA, not applicable.
Model based on Akaike information criteria. Odds ratios were computed for a change of 1 for continuous variables. Analysis includes patients who had withdrawal of care.