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. 2022 Mar 15;5(3):e221103. doi: 10.1001/jamanetworkopen.2022.1103

Table 3. Multiple Logistic Regression of Characteristics of Patients With ICH Comparing Odds of Neurologic Disability or Mortality After ICHa.

Variable Estimate (SE) Odds ratio (95% CI) P value
Log of ICH volume 1.01 (0.08) 2.74 (2.36-3.19) <.001
ICH location
Brainstem 1.39 (0.28) 4.03 (2.34-6.95) <.001
Cerebellum −0.53 (0.24) 0.59 (0.37-0.94) .03
Deep NA 1 [Reference] NA
Lobar −1.53 (0.17) 0.22 (0.16-0.30) <.001
Prestroke mRS score 0.48 (0.07) 1.62 (1.41-1.87) <.001
Admission GCS score −0.12 (0.02) 0.88 (0.85-0.92) <.001
Age, per 1-y increase 0.04 (0.006) 1.04 (1.02-1.05) <.001
Presence of infection 0.62 (0.13) 1.85 (1.42-2.41) <.001
Hematoma expansion 0.79 (0.18) 2.20 (1.55-3.13) <.001
Treatment required
ICP treatment 0.74 (0.18) 2.09 (1.46-3.00) <.001
Tracheostomy 1.84 (0.52) 6.31 (2.29-17.35) <.001
Intraventricular drain 0.64 (0.19) 1.89 (1.30-2.74) <.001
Total Graeb score 0.11 (0.03) 1.12 (1.05-1.18) <.001
Female sex 0.43 (0.13) 1.53 (1.19-1.98) .001
Prior use of α-2 adrenergic 0.81 (0.27) 2.24 (1.32-3.82) .003
Total van Swieten score 0.14 (0.05) 1.15 (1.04-1.26) .005
Medical history
Alzheimer or dementia 0.92 (0.30) 2.51 (1.40-4.51) .002
Migraine −0.97 (0.38) 0.38 (0.18-0.80) .01
Ischemic stroke 0.48 (0.20) 1.62 (1.11-2.37) .01
Diabetes 0.34 (0.14) 1.40 (1.07-1.83) .01
Cardiomyopathy 0.77 (0.35) 2.15 (1.08-4.27) .03
ICH 0.46 (0.27) 1.59 (0.94-2.68) .08
Hypertension 0.22 (0.18) 1.24 (0.88-1.75) .22
Total atrophy score 0.15 (0.06) 1.16 (1.03-1.31) .02
APOE 2 allele 0.36 (0.17) 1.43 (1.02-2.01) .04
Clinical seizure 0.45 (0.23) 1.56 (1.00-2.43) .05
Prior use of anticoagulants −0.24 (0.20) 0.79 (0.53-1.16) .23

Abbreviations: GCS, Glasgow Coma Scale; ICH, intracerebral hemorrhage; ICP, intracranial pressure; mRS, modified Rankin Scale; NA, not applicable.

a

Model based on Akaike information criteria. Odds ratios were computed for a change of 1 for continuous variables. Analysis includes patients who had withdrawal of care.