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. 2022 Mar 1;9(3):e27244. doi: 10.2196/27244

Table 1.

Study quality assessment.

Reference Q1a Q2b Q3c Q4d Q5e Q6f Q7g Q8h Q9i Q10j Q11k Q12l Q13m Q14n Total Score Rank
Wang et al [21], 2013 1 1 1 1 1 0 1 1 1 1 1 0 1 1 12 high
Burdisso et al [14], 2019 1 1 1 1 1 0 1 1 1 1 1 0 1 1 12 high
Nguyen et al [22], 2014 1 0 0 1 1 0 1 1 1 1 1 0 1 1 10 medium
Fatima et al [23], 2018 1 0 0 1 1 0 1 1 1 1 1 0 1 1 10 medium
Tung & Lu [15], 2016 0 0 1 1 1 0 1 1 1 1 1 0 0 1 9 medium
Husseini Orabi et al [24], 2018 1 0 1 1 1 0 1 1 1 1 1 0 0 1 10 medium
Islam et al [19], 2018 1 1 0 1 1 0 1 1 1 1 1 1 0 1 11 high
Shen et al [6], 2017 0 1 0 1 0 0 1 1 1 1 1 1 0 1 9 medium
De Choudhury, Gamon [25], et al, 2013 0 0 1 1 1 0 1 1 1 1 1 0 1 1 10 medium
Mariñelarena-dondena et al [26], 2017 0 1 1 1 1 0 1 1 1 1 1 0 0 1 10 medium
Tsugawa et al [27], 2015 1 1 0 1 1 1 1 1 1 1 1 1 1 1 13 high
Chen et al [28], 2018 0 0 0 0 0 0 1 1 1 1 1 0 0 1 6 low
De Choudhury, Counts [29], et al, 2013 0 0 0 1 1 0 1 1 1 1 1 1 0 1 9 medium
Dinkel et al [30], 2019 0 0 0 0 0 0 1 1 1 1 1 0 0 1 6 low
Sadeque et al [7], 2017 1 1 1 1 1 0 1 1 1 1 1 1 0 1 12 high
Shatte et al [31], 2020 1 1 1 1 1 1 1 0 1 1 1 0 1 1 12 high
Li et al [32], 2020 1 1 1 1 0 1 1 0 1 1 1 0 1 0 10 medium

aQ1: Was the research question or objective in this paper clearly stated?

bQ2: Was the study population clearly specified and defined?

cQ3: Was the participation rate of eligible persons at least 50%?

dQ4: Were all the subjects selected or recruited from the same or similar populations? Were inclusion and exclusion criteria for being in the study prespecified and applied uniformly to all participants?

eQ5: Was a sample size justification, power description, or variance and effect estimates provided?

fQ6: Were the exposure(s) of interest measured before the outcome(s) were measured?

gQ7: Was the timeframe sufficient so that one could reasonably expect to see an association between exposure and outcome if it existed?

hQ8: For exposures that can vary in amount or level, did the study examine different levels of the exposure in relation to the outcome?

iQ9: Were the exposure measures clearly defined, valid, reliable, and implemented consistently across all study participants?

jQ10: Were the exposure(s) assessed more than once over time?

kQ11: Were the outcome measures clearly defined, valid, reliable, and implemented consistently across all study participants?

lQ12: Were the outcome assessors blinded to the exposure status of participants?

mQ13: Was loss to follow-up after baseline 20% or less?

nQ14: Were key potential confounding variables measured and their impact on the relationship between exposure(s) and outcome(s) statistically adjusted for?