Table 2.
Cardiometabolic Risk Factors Stratified by Obesity and NAFLD Status Using the Comprehensive NAFLD Score
| Variable | Subjects without NAFLD OR (95% CI) | Obese subjects with NAFLD | Lean subjects with NAFLD | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |||
| Hypertension | 1.00 (reference) | 3.23 (2.78–3.73) | <0.001 | 5.40 (4.37–6.68) | <0.001 | |
| Diabetes mellitus | 1.00 (reference) | 5.40 (4.37–10.29) | <0.001 | 8.00 (6.22–10.29) | <0.001 | |
| Chronic kidney disease | 1.00 (reference) | 1.85 (1.37–2.50) | <0.001 | 1.50 (1.01–2.23) | 0.043 | |
| Hyper-LDL cholesterolemia | 1.00 (reference) | 2.24 (1.94–2.59) | <0.001 | 2.09 (1.71–2.55) | <0.001 | |
| Hypo-HDL cholesterolemia | 1.00 (reference) | 2.94 (2.55–3.39) | <0.001 | 4.29 (3.48–5.31) | <0.001 | |
| Hypertriglyceridemia | 1.00 (reference) | 5.46 (4.72–6.30) | <0.001 | 10.29 (8.29–12.76) | <0.001 | |
| Proteinuria | 1.00 (reference) | 2.90 (1.76–4.77) | <0.001 | 3.01 (1.61–5.61) | 0.001 | |
Adjusted for age and sex.
NAFLD, nonalcoholic fatty liver disease; OR, odds ratio; CI, confidence interval; LDL, low-density lipoprotein; HDL, high-density lipoprotein.