Table IV.

Inflammatory and cartilage biomarkers in serum and synovial fluid in OA patients

Variable	Serum*	Synovial fluid*	Fold change	P-value
MMP-1 [ng/ml]	4.83	45.32	9.39	≤ 0.001
MMP-3 [ng/ml]	23.06	414.12	17.96	≤ 0.001
PG-AG [ng/ml]	4689.32	87653.73	18.69	≤ 0.001
IL-6 [pg/ml]	7.01	843.17	120.28	≤ 0.001
IL-18 [pg/ml]	106.00	549.49	5.18	0.0001
IL-20 [pg/ml]	17.80	34.94	1.96	0.0281
COMP [ng/ml]	2315.61	15822.69	6.83	< 0.001

^*The values are given as a mean.