Table 1.
The serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities (IU/L), and Troponin T (ng/L), urea (mmol/L), creatinine (mmol/L) and TNFα (pg/mL) concentrations in rats from control (C), sepsis (S) and meldonium + sepsis (M + S) groups. The number of animals per experimental group: n = 8. The data are given as mean ± standard error of the mean. Minimal significant level: p < 0.05. Significantly different: a with respect to the C group; b with respect to the S group.
| C Group | S Group | M + S Group | |
|---|---|---|---|
| AST | 271.15 ± 13.93 | 288.10 ± 18.12 a | 212.83 ± 4.11 a,b |
| ALT | 65.18 ± 3.88 | 91.71 ± 2.32 a | 62.45 ± 1.62 b |
| ALP | 122.25 ± 4.49 | 164.50 ± 5.49 a | 166.67 ± 3.86 a |
| Troponin T | 31.25 ± 1.93 | 124.28 ± 2.99 a | 64.66 ± 1.62 a,b |
| Urea | 5.19 ± 0.13 | 11.76 ± 0.42 a | 7.83 ± 0.35 a,b |
| Creatinine | 45.03 ± 0.67 | 50.69 ± 1.62 | 47.88 ± 0.73 |
| TNFα | 11.32 ± 1.73 | 34.13 ± 2.57 a | 17.60 ± 2.11 a,b |