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. Author manuscript; available in PMC: 2022 Mar 16.
Published in final edited form as: Res Synth Methods. 2021 Apr 26;12(5):630–640. doi: 10.1002/jrsm.1488

Figure 2: An illustration of the 95% reference interval estimated by the mixture distribution method:

Figure 2:

The blue dashed curves are the estimated densities for 5 studies weighted by the sample sizes, and the solid black curve represents the pooled population distribution density. The 95% reference interval is the region of x-axis between two vertical lines, and the sum of area under each blue curve outside the vertical line on each side is equal to 0.025