Table 1. Macromolecular Targets Selected for CLM Fine-Tuning^a.

CHEMBL ID	target	protein classification
CHEMBL1836	prostanoid EP4 receptor	G protein-coupled receptor
CHEMBL1945	melatonin receptor 1A	G protein-coupled receptor
CHEMBL1983	serotonin 1D (5-HT1D) receptor	family A G protein-coupled receptor
CHEMBL202	dihydrofolate reductase	oxidoreductase
CHEMBL3522	cytochrome P450 17A1	cytochrome P450
CHEMBL4029	interleukin-8 receptor A	family A G protein-coupled receptor
CHEMBL5073	CaM kinase I delta	kinase
CHEMBL5137	metabotropic glutamate receptor 2	G protein-coupled receptor
CHEMBL5408	serine/threonine-protein kinase TBK1	kinase
CHEMBL5608	NT-3 growth factor receptor	kinase

^aChEMBL target identifier, generic target name, and protein classification based on the respective ChEMBL target report card.