TABLE 3.
Changes in echocardiographic indexes
| Variables | 0W | 4W | p | 12W | p |
|---|---|---|---|---|---|
| LVDd (mm) | 58.0 (56.0‐60.5) | 54.6±6.7 | .168 | 55.1±4.7 | .209 |
| LVDs (mm) | 35.1±6.2 | 34.3±7.8 | .395 | 33.7±6.4 | .306 |
| IVSd (mm) | 14.3±2.1 | 14.3±1.7 | .541 | 14.0±1.4 | .952 |
| LVM (g) | 416.5±107.3 | 401.3±143.4 | .300 | 390.0±106.8 | .137 |
| LVM index (g/m2) | 206.2±30.4 | 194.6±48.4 | .135 | 192.0±39.6 | .198 |
| LVEDV (ml) | 133.2±25.9 | 138.7±27.9 | .437 | 122.6±26.1 | .251 |
| LVEDV index (ml/m2) | 72.5±16.5 | 75.7±16.9 | .387 | 66.6±14.9 | .231 |
| LVESV (ml) | 62.8±15.2 | 65.9±14.8 | .361 | 53.3±11.0 | .139 |
| LVEF (%) | 53.2±5.9 | 52.5±4.6 | .457 | 56.3±4.7 | .125 |
| LVGLS (%) | ‐14.9±3.0 | ‐15.1±3.0 | .300 | ‐15.9±1.7 | .042* |
| E average (cm/s) | 81.8±30.6 | 68.8±22.2 | .057 | 66.4±17.6 | .026* |
| E´ average (cm/s) | 6.0(4.5‐7.0) | 4.6±1.2 | .110 | 5.4±1.5 | .458 |
| E/E’ ratio | 14.9±5.8 | 15.6±5.4 | .957 | 12.9±4.2 | .221 |
Abbreviations: LVDd, left ventricular diastolic diameter; LVDs, left ventricular systolic diameter; IVSd, inter‐ventricular septal thickness at diastole; LVM, left ventricular mass; LVEDV, left ventricle end‐diastolic Volume; LVESV, left ventricular end‐systolic volume; LVEF, left ventricular ejection fraction; LVGLS, global longitudinal strain of left ventricle; E, peak velocities of trans‐mitral early; E’, septal and lateral peak early diastolic velocity; E/E’, trans‐mitral to mitral annular early diastolic velocity. 0W, week0; 4W, week4; 12W, week12. The results represent the mean the mean ± SEM or medians (P25, P75). *, p < .05, 12W compared with 0W.