Table 2.
Potential predictors of wanting to discontinue antipsychotic medication
| Potential predictor variable | % or Mean value (SD) in people who want to stop antipsychotics | % or Mean value (SD) in people who do not want to stop antipsychotics | Mean difference/Odds ratio (95% CI) | P value of difference* |
|---|---|---|---|---|
| Gender |
68.6% male (n = 94) |
61.0% male (n = 75) |
1.40 (.839–2.33) | .197 |
| Age |
45.90 (11.32) (n = 135) |
46.57 (12.02) (n = 122) |
−0.67 (−3.54–2.20) | .646 |
| Marital status | 73.2% single/unmarried | 63.7% single / unmarried | 1.55 (.87–2.76) | .173 |
| Ethnicity | 50% white British or other | 52.2% white British or other | 0.92 (.55–1.54) | .846 |
| Employment | 85.3% unemployed | 83.2% unemployed | 0.85 (.40–1.82) | .824 |
| Time taking antipsychotics |
14.68 (9.57) (n = 65) |
17.32 (10.57) (n = 142) |
−2.64 (−5.67 to .391) | .087 |
| Antipsychotic preparation | 44.4% oral only | 51.4% oral only | 0.76 (.45–1.28) | .366 |
| Dose of antipsychotics (in chlorpromazine equivalents) |
328.91 (275.46) (n = 64) |
365.01 (268.04) (n = 152) |
−36.10 (−115.48 to 43.27) | .371 |
| DAI totala |
−.86 (5.16) (n = 74) |
4.32 (4.11) (n = 165) |
−5.18 (−6.53 to −3.83) | <.001 |
*p values are derived from t-tests for continuous variables and Chi squared tests for categorical variables; bold indicates significance at the P < .05 level
aDrug Attitude Inventory