Table 1.
Association between AMIGO2 expression and clinicopathological factors. The chi-square test and Fisher's exact test were used for the statistical analyses
| parameter | AMIGO2 expression | P value | ||
|---|---|---|---|---|
| negative | positive | |||
| n = 99 | n = 29 | |||
| Age(years) | < 70 | 44 | 14 | 0.715 |
| ≥ 70 | 55 | 15 | ||
| Sex | male | 71 | 26 | 0.047a |
| female | 28 | 3 | ||
| BMI | < 25 | 82 | 26 | 0.283 |
| ≥ 25 | 17 | 3 | ||
| Neoadjuvant chemotherapy | yes | 9 | 2 | 0.526 |
| no | 90 | 27 | ||
| Adjubant chemotherapy | yes | 30 | 11 | 0.439 |
| no | 69 | 18 | ||
| Stage (UICC 7th) | I | 48 | 14 | 0.086 |
| II | 28 | 3 | ||
| III | 20 | 10 | ||
| IV | 3 | 2 | ||
| Histlogical type | poor/sig | 54 | 10 | 0.057 |
| well/mod/other | 45 | 19 | ||
| Vascular invasion | negative | 42 | 5 | 0.013 a |
| positive | 57 | 24 | ||
| Lymphatic invasion | negative | 34 | 7 | 0.300 |
| positive | 65 | 22 | ||
| pT | I/II | 56 | 16 | 0.894 |
| III/IV | 43 | 13 | ||
| pN | 0 | 58 | 15 | 0.512 |
| 1 | 41 | 14 | ||
| CEA (ng/mL) | < 5 | 78 | 20 | 0.272 |
| ≥ 5 | 21 | 9 | ||
| CA19-9 (U/mL) | < 35 | 87 | 26 | 0.545 |
| ≥ 35 | 12 | 3 | ||
| Liver metastasis | presence | 7 | 8 | 0.006 a |
| absence | 92 | 21 | ||
| Peritoneal dissemination | presence | 12 | 8 | 0.047 a |
| absence | 87 | 21 | ||
BMI body mass index, sig/poor/mod/well signet-ring cell/poorly/moderately/well differentiated, pT/N pathological T/N stage, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen19-9, astatistically significant, the chi-square test and Fisher's exact test were used for the statistical analyses