Correlations between immune cells level and clinicopathological parameters of oral squamous cell carcinoma of the mobile tongue (OTSCC) patients. (A, B) Differential expression of T regs and dendritic cells resting fraction were significantly negatively related to tumor size (P=0.025, P=0.002; T1–2, n=57, T3–4, n=67), while (C) CD4 memory resting T cells were significantly positively correlated with lymph node size (P=0.002, N0=52, N1–3=66). (D) The barplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (E) The dotplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (* P<0.05, ** P<0.01, *** P<0.001).