Comparison 1. Tranexamic acid versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Mortality	3	260	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.14, 7.30]
2 Transfusion	3	260	Risk Ratio (M‐H, Fixed, 95% CI)	0.70 [0.52, 0.94]
3 Deep venous thrombosis	2	191	Risk Ratio (M‐H, Fixed, 95% CI)	2.29 [0.68, 7.66]
4 Pulmonary embolism	1	110	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Myocardial Infarction	1	110	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6 Stroke	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only