Moghaddam 2011.

Methods	Double blind clinical trial
Participants	Population: 60 patients with femoral bone fracture Setting: Iran Date the study was conducted: not reported
Interventions	Intervention: tranexamic acid 10 mg/kg bolus dose and 1 mg/kg infusion during operation Control: saline (same dose)
Outcomes	Blood loss and blood transfusion. No deaths reported.
Notes	The report is an abstract and does not present how many patients were randomised in each group so no data can be analysed.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not enough data reported
Allocation concealment (selection bias)	Unclear risk	Not enough data reported
Blinding of outcome assessment (detection bias) Mortality	Unclear risk	Not enough data reported
Blinding of outcome assessment (detection bias) Transfusion	Unclear risk	Not enough data reported
Blinding of outcome assessment (detection bias) Complications	Unclear risk	Not enough data reported
Incomplete outcome data (attrition bias) Mortality	Unclear risk	Not enough data reported
Incomplete outcome data (attrition bias) Transfusion	Unclear risk	Not enough data reported
Incomplete outcome data (attrition bias) Complication	Unclear risk	Not enough data reported
Selective reporting (reporting bias)	Unclear risk	No protocol available
Other bias	Unclear risk	‐