Table 1.

Effect of deletion of VWA8 on selected fuel metabolites.

	Glucose		Palmitate
	WT	KO	WT	KO
Glucose	1.88±0.35**	1.99±0.21**	0.86±0.02	1.02±0.04
Glucose 6-phosphate	6.03±0.28**	2.95±0.52**§	2.12±0.47	0.25±0.06§
2-Phospho-glycerate	2.02±0.59**	1.43±0.66**	0.10±0.02	0.08±0.0
Pyruvate	1.75±0.23**	1.37±0.19**	0.97±0.13	0.88±0.15
Palmitate	0.09±0.29**	0.17±0.11**	1.31±0.15	1.20±0.35
Palmitoyl-carnitine	0.003±0.001**	0.002±0.0001**	1.52±0.11	1.99±0.30

Data are raw area counts normalized to protein concentration. WT, CRISPR wildtype AML12 cells; KO, VWA8 null AML12 cells.

^**P<0.01 Glucose vs. Palmitate

^§P<0.01 KO vs. WT; WT, wildtype; KO, VWA8 null cells. Statistical comparison of wildtype and VWA8 null cells was performed using non-paired t-tests.