Figure 1.

Demonstration of the plaque analysis method. Stretched multiplanar reconstruction of the left anterior descending (LAD) artery and quantification graph of the LAD. Yellow shaded regions correspond to analyzed segments and blue shaded regions correspond to plaques. Components of coronary plaque are shown as follows: lipid-rich (low-computed tomographic attenuation) plaque components are shown in red; fibro-fatty tissue is shown in light green; fibrous tissue is shown in dark green; calcium is shown in white. Example 1: One of the siblings had plaques; plaques were analyzed, and for the other sibling, segments in the same location and same length were analyzed. Example 2: Both siblings had plaques; all the segments were analyzed which included any plaque in either of the siblings. In case neither of the siblings had coronary artery disease (CAD), a plaque volume of 0-0 was used.