Timeline of events during the hospital admission and ceftazidime-avibactam treatment received by patients A, B, and C. Yellow bars represent duration of treatment with ceftazidime-avibactam. Samples with the framed dates are those that were subsequently tested for the screening of KPC-carbapenemase and analyzed by whole-genome sequencing. CAZ/AVI, ceftazidime-avibactam; CP, carbapenemase; ESBL, extended-spectrum β-lactamase.