TABLE 1.
Antibiotic susceptibility results in KPC-producing K. pneumoniae isolates
| Isolate | MIC (mg/L) for:a |
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PTZ | AZT | CTX | CAZ | FEP | IMP | ERT | MER | C/T | FTB | CAZ/AVI | AZT/AVI | IMI/REL | MER/VAB | FDC | CIP | GEN | TOB | AMK | COL | FOS | TGC | |
| A-1 | >64/4 | >32 | >32 | >32 | 32 | 16 | >4 | 8 | 32 | 0.5 | 2 | 0.12 | 0.25 | ≤0.06 | 0.5 | >2 | >8 | >8 | ≤8 | >4 | 64 | 1 |
| A-2 | >64/4 | >32 | >32 | >32 | 32 | ≤1 | ≤0.5 | ≤ 0.12 | >32 | 2 | 32 | 0.06 | 0.25 | ≤0.06 | 1 | >2 | >8 | >8 | 32 | >4 | >64 | 1 |
| B-1 | >64/4 | >32 | >32 | >32 | >32 | 16 | >4 | >16 | >32 | 1 | 2 | 0.25 | 0.25 | ≤0.06 | 1 | >2 | >8 | >8 | 16 | >4 | 64 | 2 |
| B-2 | >64/4 | >32 | >32 | >32 | 32 | ≤1 | ≤0.5 | ≤ 0.12 | >32 | 1 | 8 | 0.25 | 0.25 | ≤0.06 | 2 | >2 | >8 | >8 | 16 | >4 | >64 | 2 |
| C-1 | >64/4 | >32 | >32 | >32 | >32 | 16 | >4 | >16 | >32 | 0.5 | 1 | 0.12 | 0.5 | ≤0.06 | 1 | >2 | >8 | >8 | ≤8 | ≤1 | >64 | 2 |
| C-2 | 32/4 | >32 | >32 | >32 | 16 | ≤1 | ≤0.5 | ≤ 0.12 | >32 | 0.5 | 8 | 0.06 | 0.25 | ≤0.06 | 2 | >2 | >8 | >8 | ≤8 | ≤1 | >64 | 2 |
a
PTZ, piperacillin-tazobactam; CTX, cefotaxime; CAZ, ceftazidime; FEP, cefepime; AZT, aztreonam; IMP, imipenem; ERT, ertapenem; MER, meropenem; CIP, ciprofloxacin; GEN, gentamicin; TOB, tobramycin; AMK, amikacin; COL, colistin; FOS, fosfomycin; TIG, tigecycline; C/T, ceftolozane-tazobactam; CAZ/AVI, ceftazidime-avibactam; AZT/AVI, aztreonam-avibactam; MER/VAB, meropenem-vaborbactam; IMI/REL, imipenem-relebactam; FDC, cefiderocol; FTB, cefepime-taniborbactam.