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. 2021 Sep 16;37(2):411–424. doi: 10.3904/kjim.2020.438

Figure 5.

Figure 5

Effects of treatment with mesenchymal stem cells (iMSCs) or iMSC-derived exosome (iExo) on the mRNA levels of antioxidant and inflammatory genes in renal ischemia reperfusion (I/R) injury mouse model. Quantitative real-time polymerase chain reaction analysis of (A) superoxide dismutase 2 (SOD2), (B) catalase, (C) nuclear factor erythroid-2-related factor (NRF2), (D) nuclear factor κB (NF-κB), (E) tumor necrosis factor-α (TNFα), (F) interferon γ (IFNγ), (G) interleukin 1β (IL-1β), and (H) F4/80 expression in kidney tissues. All results are representative of at least three independent experiments. Data are presented as mean ± standard error. GAPDH, glyceraldehyde 3-phosphate dehydrogenase. ap < 0.05 vs. Sham, bp < 0.05 vs. Sham + iMSC, cp < 0.05 vs. Sham + iExo, dp < 0.05 vs. I/R, ep < 0.05 vs. I/R + iMSC.