Table 2.
Regression Analysis of Variables Associated with Obesity (BMI ≥30 Kg/M2)
| Variables | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age, years | ||||||
| ≤40 | 1 | 1 | ||||
| >40 | 2.03 | 1.69–2.43 | <0.001 | 1.90 | 1.49–2.43 | <0.001 |
| Menopausal status | ||||||
| Pre/perimenopause | 1 | 1 | ||||
| Postmenopause | 1.65 | 1.37–1.99 | <0.001 | 1.37 | 1.06–1.76 | 0.01 |
| History of OCP | 1.34 | 1.09–1.67 | 0.006 | 1.33 | 1.05–1.67 | 0.01 |
| Screen detected | 1.05 | 0.81–1.37 | 0.68 | |||
| ER+ vs ER- | 0.97 | 0.82–1.12 | 0.97 | |||
| PR+ vs PR- | 1.11 | 0.94–1.32 | 0.19 | |||
| HER2+ vs HER2- | 0.82 | 0.68–0.98 | 0.03 | 0.73 | 0.59–0.92 | <0.01 |
| TN vs others | 1.05 | 0.85–1.30 | 0.60 | |||
| Grade ≤II vs III | 0.94 | 0.80–1.12 | 0.54 | |||
| Clinical stage I/II vs III | 1.35 | 1.14–1.61 | 0.001 | 1.25 | 1.01–1.56 | 0.04 |
| NAC vs no NAC | 1.07 | 0.90–1.27 | 0.43 | |||
| MRM vs BCS | 0.97 | 0.77–1.23 | 0.83 | |||
| Radiation vs no radiation | 1.45 | 1.16–1.81 | 0.001 | 1.63 | 1.22–2.20 | 0.001 |
| Axillary dissection | 1.19 | 0.94–1.50 | 0.14 | |||
| ACT vs no ACT | 0.90 | 0.76–1.07 | 0.27 | |||
Abbreviations: ACT, adjuvant chemotherapy; BCS, breast conservative surgery; BMI, body mass index; CI, confidence interval; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; MRM, modified radical mastectomy; NAC, neoadjuvant chemotherapy; OR, odds ratio; PR, progesterone receptor; TN, triple-negative.